About Tofe ProductsTofe Products side effects
Common
Side Effects of Tofe are Headache, Diarrhea, High blood pressure, Rash, Pneumonia, Bronchitis (inflammation of the airways), Tuberculosis, Nasopharyngitis (inflammation of the throat and nasal passages), Urinary tract infection, Cellulitis, Herpes zoster, Diverticulitis, Appendicitis, Anemia (low number of red blood cells), Cough, Abdominal pain, Vomiting, Nausea, Stomach inflammation, Dyspepsia, Joint pain, Fever, Peripheral edema, Fatigue.
How Tofe Products workTofacitinib is an Janus kinase inhibitor. It works by blocking the action of the enzyme, Janus kinase. This decreases inflammation and joint damage in rheumatoid arthritis.
In Depth Information for Tofe Products Patient Concerns about Tofe ProductsFrequently asked questions about Tofe ProductsFrequently asked questions about TofacitinibQ. Can I take Tofe Tablet if I have liver problems?
Inform your doctor if you have liver problems, before starting Tofe Tablet. This is done because in some cases Tofe Tablet may cause an increase in liver enzymes. Therefore, your liver function needs to be investigated before starting Tofe Tablet. Although, Tofe Tablet can be given to patients with mild to moderate liver function impairment, but should not be prescribed to patients with severe liver impairment.
Q. Can Tofe Tablet cause cancer?
Tofe Tablet may increase the chances of developing the risk of certain cancers (lymphoma and other cancers including skin cancers) by affecting the working of the immune system. Hence, inform your doctor if you ever had or have any type of cancer.
Q. What is Tofe Tablet used for?
Tofe Tablet is approved for use in people with moderate to severe rheumatoid arthritis. It is an inflammatory disease of the joints. It is used if previous therapy did not work well or did not suit the patient. However, it can also be used earlier in treatment if the person does not respond well to the prescribed drugs. It can be used alone or together with some other medicines, such as methotrexate.
Q. How long does it take for Tofe Tablet to start working?
Tofe Tablet usually takes about 2 to 8 weeks before you start feeling better, and it can take 3 to 6 months to feel the maximum effect of this medication.
Q. Do I need to get any investigations done before starting Tofe Tablet?
You may need to get your blood tests done before you start Tofe Tablet or while you are taking it. Blood tests are done in order to check if you have a low red blood cell count (anemia), low white blood cell count (neutropenia or lymphopenia), high blood fat (cholesterol) or high levels of liver enzymes. It also helps to ensure that treatment with Tofe Tablet is not causing problems. In addition to this, your doctor may advise you to get tested for tuberculosis before starting Tofe Tablet, as using Tofe Tablet may make an existing infection worse.
Q. Can Tofe Tablet cause infections?
Tofe Tablet is a medicine that affects your immune system. This may reduce your ability to fight infection and may increase the risk of getting a serious infection including tuberculosis. It may also include infections caused by severe fungal, bacterial or viral infections that spread through the body. In some cases, these infections can be life-threatening and may even cause death. Hence, it is advised to treat these infections in a hospital.
Q. If I am already taking tocilizumab, can I take Tofe Tablet?
No, you should not take tocilizumab along with Tofe Tablet. Tofe Tablet affects the immune system, so you should avoid taking it with any other immunity-affecting medicine. Taking both medicines together can further increase the risk of infection and may lead to further complications.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 13th Jun 2023.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.
Substitute brands for Tofe
Tocib
Ankaa Pharmaceutical
FAQs
Tofe Tablet is used to treat moderate to severe rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. It helps decrease pain, tenderness, and swelling in the joints by reducing inflammation. It also helps slow the progression of bone and joint damage.
What are the side effects of Tofatas? ›
The most common side effects of Tofatas Tablet include upper respiratory tract infections, headache, diarrhea, and nasopharyngitis. There are other less common side effects, some of them serious, including blood clots and tears in the stomach or intestine wall. These need urgent medical attention.
What are the precautions for tofacitinib? ›
Your body's ability to fight infections may be reduced while you are using tofacitinib. It is very important that you call your doctor at the first sign of an infection. Check with your doctor right away if you have a fever, chills, cough, flu-like symptoms, or unusual tiredness or weakness.
What is tofe? ›
Tofe Tablet is approved for use in people with moderate to severe rheumatoid arthritis. It is an inflammatory disease of the joints. It is used if previous therapy did not work well or did not suit the patient.
Does tofacitinib cause weight gain? ›
Tofacitinib may cause weight gain, a rare side effect reported in several studies. We reported six cases to the Indian Pharmacopoeia Commission with unique ID numbers IN-IPC-300735393, IN-IPC-300735401, IN-IPC-300735421, IN-IPC-300735665, IN-IPC-300744097, and IN-IPC-300744286.
What are the disadvantages of tofacitinib? ›
It's possible that tofacitinib may increase the risk of blood clots in the legs, called deep vein thrombosis. These can sometimes move to the lungs, which is called pulmonary embolism. The risk is likely to be greater if you've had either of these before.
What is the cost of Tofatas? ›
Tofatas 5 Mg Tablets at Rs 333/bottle | Tofacitinib Tablets in Mumbai | ID: 23424020312.
What is the FDA warning on tofacitinib? ›
On September 1, 2021, the FDA issued a drug safety communication and required revisions to the Boxed Warning, FDA's most prominent warning, for tofacitinib/XR, baricitinib, and upadacitinib to include information about the risk of serious heart-related events, cancer, blood clots, and death.
What is the success rate of tofacitinib? ›
Consistent with previous literature, these data indicate that tofacitinib is effective for AA treatment, with an all-cause response rate of 95% at 6 months, with more than one-third of patients achieving a CR.
What foods should I avoid while taking Xeljanz? ›
To learn about the side effects of Xeljanz, see this article. Due to this risk, your doctor may recommend avoiding grapefruit products during Xeljanz treatment. If you have questions about Xeljanz interactions with food, talk with your doctor for more information.
The efficacy and safety of tofacitinib 5 and 10 mg twice daily (BID) administered as monotherapy or in combination with csDMARDs, mainly methotrexate (MTX), in patients with moderately to severely active RA, have been demonstrated in phase II,4–8 phase III9–14 and phase IIIb/IV15 studies of up to 24 months' duration, ...
Can tofacitinib affect the kidneys? ›
Long-term tofacitinib continued to be effective in preventing renal allograft acute rejection and preserving renal function.
Is tofe 5 a steroid? ›
Tofe 5mg tablet contains the active substance tofacitinib. It is a disease-modifying anti-rheumatoid drug (DMARDs) that belongs to the class immunomodulators.
What does tofacitinib do to the liver? ›
According to clinical trial studies, serum aminotransferase elevations occurs in 28–34% of patients who received tofacitinib. In these studies mild and transient liver involvement was described, and no case of severe liver damage was reported.
Does tofacitinib suppress the immune system? ›
Tofacitinib is an FDA-approved immunomodulating small molecule which suppresses immune cell function by blocking proinflammatory cytokine signaling.
Is tofacitinib a pain killer? ›
Tofacitinib is used alone or with other medications to treat rheumatoid arthritis (condition in which the body attacks its own joints causing pain, swelling, and loss of function) in adults who are unable to take or did not respond to one or more tumor necrosis factor (TNF) inhibitor medication(s).
What are the benefits of tofacitinib? ›
It helps to decrease pain/tenderness/swelling in the joints. Tofacitinib is also used to treat a certain bowel disease (ulcerative colitis). It helps to reduce symptoms of ulcerative colitis such as diarrhea, rectal bleeding, and stomach pain.
Does tofacitinib make you sleepy? ›
Fatigue is a possible side effect of Xeljanz and Xeljanz XR. However, it's not known how often this side effect occurred in clinical studies. Fatigue may also be a symptom of more serious side effects of Xeljanz and Xeljanz XR, including: serious infections*
